Kim jest dr Alicja Zobel?

Dr. Zobel is a professor of biochemistry, cell physiology and photo-chemistry at the University of Warsaw (Poland), Trent University (Canada) and visiting professor at Cornell University (U.S.A.). She holds two patents for anti-cancer natural products and was the secretary of the Phytochemical Society of North America for seven years. As a researcher, Dr. Zobel has applied her interest in the health of plant cells to the health of human cells, studying and teaching how every cell must be nourished, protected from bad environmental influences, and freed of harmful toxins, leading to a healthy body.

Dr. Alicja Zobel, PhD. Article Page • Bio 2 • Curriculum Vitae 3 • Symposiums Attended 4-5 • Publications 6-8 • Review Articles 9 • Clinical support of Nutritional Supplementation 10 • Minerals & Human Health by: Dr. Zobel 11 2981-2nd Line Rd., RR #1-Warsaw, Ontario CANADA K0L 3A0 Phone: 1(705)652-6145 or: 800-377-0084 Fax: (801)8818659 Email: DrZobel@MineralSmart.com Dr. Alicja Zobel, PhD Bio World renowned researcher, Dr. Alicja Zobel originally from Poland, residing in Canada is concerned about how the health of our bodies is affected by our diet, and which specific nutrients our bodies must have to stay well. Dr. Zobel is a professor of biochemistry, cell physiology and photo-chemistry at the University of Warsaw (Poland), Trent University (Canada) and visiting professor at Cornell University (U.S.A.). She holds two patents for anti-cancer natural products and was the secretary of the Phytochemical Society of North America for seven years. As a researcher, Dr. Zobel has applied her interest in the health of plant cells to the health of human cells, studying and teaching how every cell must be nourished, protected from bad environmental influences, and freed of harmful toxins, leading to a healthy body. Dr. Zobel travels extensively in her research, collaborating with scientists at seven other international institutions. She participates in six to ten scientific meetings and colloquiums each year and gives free public seminars at Trent University (Canada) and Lublin Medical Academy (Poland). She has a phone-in program on Trent University Radio, and a book/calendar produced in response to her listeners. Mineral Smart Inc. ~ 1-800-377-0084 CURRICULUM VITAE ALICJA MARIA ZOBEL R.R. 9, Peterborough, Ontario K9J 6Y1, Canada Email: DrZobel@MineralSmart.com Tel. 1-800-377-0084 Fax: 1-801-881-8659 SUMMARY Polish Canadian professor of biochemistry, cell physiology and phytochemistry since 1971. Shifted the interest from the health of plant cells to human cell health, since each and every cell must be nourished, protected from bad environmental influences and freed from harmful toxins; this leads to healthy body. For seven years secretary of the Phytochemical Society of North America, and has looked for anticancer natural products (two patents), and antioxidants in our diet. Organizer of several scientific meetings and participant in six to ten such meetings a year. Member of New York Academy of Science since and elected as the Woman Scientist of the year 2002. PROFESSIONAL EXPERIENCE Education: • Master's degree Warsaw University, 1971. Thesis topic: "Development of the tannin-containing cells in shoots of Sambucus racemosa L." • Doctor of Philosophy, Warsaw University, 1979. Thesis topic: "Ontogenesis of tannin coenocytes in Sambucus racemosa and some other Sambucus species. Positions held: 1971-74 Research worker, Warsaw University, Laboratory of General Botany. 1974-86 Professor, Department of Plant Anatomy and Cytology, Warsaw University. 1986-87 Visiting Professor, Cornell University, Geneva NY, USA 1987-89 Research Associate, Trent University. 1989- Conjunct Associate Professor, Trent University Current and previous research interests – Botany, Phytochemistry and Ecology: 1. Mechanisms of differentiation (a) differentiation of promeristem (b) appearance and ontogenesis of different idioblastic cells specialized in their physiology (c) histological modifications as an influence of ecological environment, i.e., adaptations to the environment by water plants and desert plants (d) modifications as the result of chemical influence, e.g., poisons such as potassium cyanide and lead, and hypoxia. 2. Localization of phenolic compounds in the plant body (a) histological identification (b) subcellular localization (c) influence of phenolic compounds on chromatin, on cell physiology, and on differentiation of callus cultures. 3. Immunochemistry: immunological labelling techniques for tracing enzymes of anthocyanin biosynthesis, and glycolysis. 4. Development of new methods for analysis of protective compounds on plant body. 5. Antioxidants and detoxification; role of glutathione acrylamids detoxification. 6. Reaction of plant tissues to environmental pollution (a) acid rain (b) salt spray (c) metal ions (d) mobilization of the defense system by the plant. 7. Identification of toxic compounds (furanocoumarins) causing photophytodermatitis, and heir localization in plant cells. 8. Seed physiology: localization of phenolic compounds in the seed coat and embryo. Autoinhibition of germination. 9. Ultraviolet reaction on plant genome and physiology. Transduction of ultraviolet into visible light. 10. Role of natural products as potential anticancer drugs. 11. Role of secondary products in plants in communication between the plant and its environment: a) attractants and repellents to insects b) antifeedants to herbivores c) phytoalexins d) allelochemicals. 12. Role of secondary metabolites in symbiotic complexes: a) of lower plants and fungi, lichens and corals; b) of higher plants and fungi. Mineral Smart Inc. ~ 1-800-377-0084 SYMPOSIA ATTENTED and papers presented (since 1998) 1. 1998 18th Annual Convention of Indian Association for cancer research and National Symposium on Molecular Biology of Cancer, New Delhi, February 19-21. Paclitaxel and coumarin as effective anticancer drug. A.M. Zobel and S. Schellenberger. 2) Different biological activities of Rhodiola rosea L. tissue and organ extracts. M. Furmanowa, A. Zobel, M. Kuras, M. Hartiwich, L. Solonicka, A. Michalak and J. Guzewska. 3) Modern methods for chromatographic determination and isolation of 10-deacetybaccatin III and other taxoids from Taxus species. K. Glowniak, T. Mroczek, M. Hajnos, and A.M. ˙Zobel. 4) Cytological and biochemical reactions of cells to free radicals and some antioxidants. A. Ruchirawat, F. Nxumallo and A.M. Zobel. 5) Features of tissue and organs cultured in vitro of some Polish Taxus species. M. Furmanowa, B. Sykeowska, J. Guzewska, A. Zobel, K. Glowniak, M. Jaziri and A. Michalak. 6) Hair analysis in cancer and control groups. A. Zobel, T. Switzer, M. Onion and S. Klein. 2. 1998 National Scientific Conference, Canadian Breast Cancer Research Initiative, Toronto, June 17-19. 1)Coumarin and flax seed oil as antimitotics. A.M. Zobel, K. Glowniak, M. Furmanowa and E. Kupidlowska. 2) Coumarin-saponin and whey protein as antimitotics. A.M. Zobel, A. Mislik, M. Podbielkowska, E. Kupidlowska, M. Waleza and A. Ruchirawat. 3. 1998 7th Conference on the Application of Chromatographic Methods in Phytochemical and Biomedical Anlysis, Lublin, Poland, June 25-27. (invited speaker) 1)Quercetin and coumarin as a mixture of comounds of antimitotic activity. A.M. Zobel, A.M. Davis and A. Ruchirawat. 2) The influence of the traffic arteries closeness on chemical composition of Achillea illfolium L. and Tanacetum vulgare L. K. Wierzchowska-Renke, S. Ivancheva and A.M. Zobel. 3) Compounds removed from plant surfaces as potential anticancer agents. J.M. Lynch, A.M. Zobel, E. Kupidlowska, K. Wierzchowska-Renke and K. Glowniak (poster). 4) Human hair analysis in cancer and control group. A.M. Zobel, T. Switzer, S. Klein and M. Onion. 5) Secondary metabolites deposited on the surface of Brassica oleracea var. acephala leaves reduce insect predation. J.M. Lynch and A.M. Zobel. 4. 1998 Second International Conference on Recycling of Trace Elements in the Environment, Warsaw, Poland, October 27-29. (invited speaker)1)The production of phenolic compounds in response to UV-A irradiation and metal ions in seedlings of Acer saccharum A.M. Zobel, P.A. Clarke, J.M. Lynch, M. Kuras, T. Tykarska and E. Kupidlowska. 5. 1998 International Symposium: Antitumour Products from Higher Plants, Universit‚ Rene Descartes, Facult‚ de Pharmacie, Paris, January 8-10. 1)Coumarins and their antimitotic action. K. Wierzchowska-Renke, E. Kupidlowska, K. Glowniak and A.M. Zobel (poster). 6. 1998 Turkey, May Antimitotic activity of medicinal plants extracts removed from the surface and interior of fresh leaves. A.M. Zobel, J.M. Lynch, E. Kupidlowska, K. ˙Wierzchowska-Renke and K. Glowniak (poster). 7. 1998 Seminar on Taxoids: Sources and Biological, Chemical and Pharmacological Aspects, Academy of Medicine, Warsaw, June 24-25. Antimitotic activity of Taxus canadensis taxoids and their mixtures with coumarins. J.M. Lynch, A.M. Zobel, E. Kupidlowska and G. Element (poster). 2) Compounds removed from plants surfaces as potential anticancer agents. J.M. Lynch, A.M. Zobel, E. Kupidlowska, K. Wierzchowska-Renke and K. Glowniak. 8. 1999 Symposium on Sustainable Management of Hemlock Ecosystems in Eastern North America, Durham, NH, U.S.A., June 22-24. Long-term scientific benefits from preserving old-growth hemlock stands at Clear Lake near Haliburton, Ontario. R. Reid, J.E. Nighswander, K.M. Somers and A.M Zobel. 2) Management of an undisturbed water ecosystem containing old growth hemlock, as a model system of Clear Lake Reserve in Ontario. A.M. Zobel, K. Cybulski, K. Glowniak, and J.E. Nighswander. 3) Phytochemistry of plants associated with 400-year-old stand of hemlock at Clear Lake Reserve, Ontario. A.M. Zobel, K. Glowniak, J.E. Lynch, S. Dudka and A. Alliota. 9. 1999 Annul Meeting, Phytochemical Society of North America, Montreal, July 10-13. 1)Coumarin, flax seed oil and whey protein as antmitotics. A.M. Zobel, K. Glowniak and M. Furmanowa. 2) The influence of aphis and UV radiation on the mineral composition of medicinal plants. K. Wierzchowska-Renke, A. Zobel, A. Dorosz, W. Dejnika and K. Glowniak. 2) The influence of ultraviolet radiation on the quantity of some taxoids in Taxus baccata var. aurea. K. Glowniak, M. Hajnos and A. Zobel. 3) Effects of Taxotere and Rhodiola rosea callus extracts on mitoses in Allium cepa roots. M. Furmanowa, M. Kuras, E. Wolska, A. Michalak, N. Urbanska and A. Zobel. Mineral Smart Inc. ~ 1-800-377-0084 10. Second World Congress on Allelopathy, Thunder Bay, ON, August 8-13 (invited speaker) 1)UV radiation influence on cell to cell interaction. M. Kuras and A.M. Zobel. 2) Localization of antioxidants as F. Nxumalo and A.M. Zobel. 2) Soil composition affecting secondary metabolites in plant root and shoot. K. Wierzchowska-Renke, S. Ivancheva and A.M. Zobel. 3) Connections between cytological localization of phenolic compounds and their allelopathic role in plant-plant interaction. A.M. Zobel. 4) Is allelopathy responsible for formation of hemlock clumps within broadleaf forest around Clear Lake near Minden, Ontario? A.M. Zobel, J.E. Nighswander, S. Narwal, K. Renke and A. Ruchirawat 11. 1999 Seminar on Medicinal Plants Under 400-year-old Hemlock, Minden, Ontario, August 15-19. Phytochemistry of medicinal plants under hemlock trees at Clear Lake Reserve. A.M. Zobel, M. Furmanowa, K. Glowniak, K. Wierzchowska-Renke and J. E. Nighswander. (invited speaker) 12. 1999 Saponins, Pulawy, Poland, September 6-8. Localization of Saponins and phenolic compounds in alfalfa cells. A.M. Zobel, K. Glowniak, W. Oleszek and K. Renke (invited speaker) 13. 1999 Pollution and Human Health, Augustow, Poland, September 6-7. Pollution influencing plant chemistry causes changes in human health. A.M. Zobel and K. Wierzchowska-Renke (invited speaker) 14. 1999 Seventh Conference on Cell Biology, Krakow, Poland, October 9-10. Influence of taxoter on meristematic cells of Allium cepa root tips. A.M. Zobel, A. Michalak, M. Furmanowa, M. Kuras and J. Bednara 15. 1999 Congress on Human Vitality and Fair on Natural Drugs, Warsaw, Poland, September 16-18. 16. 2000 International Cancer Society, Kamala, India, February 19-21. (invited speaker) 17. Mixture of paclitaxel with coumarin and whey as a potential anticancer treatment. A.M. ˙Zobel, S. Schellenberger, M. Furmanowa, K. Wierzchowska-Renke and K. Glowniak 18. 2000 Third Conference on Trace Metals: Effects on Organisms and Environment, Sopot, Poland, June 6-8. Changes in the mineral composition of Pastinaca sativa caused by heavy metal ions and UV radiation. K. Wierzchowska-Renke, K. Glowniak, A. Dorosz, A.M. Zobel and A. Gekelman 19. 2000 Second International Conference on Chromatography of Medicinal Plants, Lublin-Kazimierz, Poland, June 14-16. 1) Whey protein and coumarin offsetting chromosomal aberrations caused by pacitaxel and other taxoids removed from the surface of yew leaves. A.M. Zobel (invited speaker) 2)Stress conditions affected localization of furanocoumarins. A. Misik, A.M. Zobel, K. Renke and M. Furmanowa 20. 2000 Biotechnology, Sobieszewo, Poland, September 11-13. Glutathione level and cell health. A.M. Zobel (invited participant in panel discussion) 21. 2000 Drug in Poland, Warsaw, Poland, September 21-22. Free Radicals, glutathione and health. A.M. Zobel 22. 2000 Seminar on Nutrition for Children with Down's Syndrome, Warsaw, Poland, September 25. Whey protein in diet. A.M. Zobel (invited speaker) 23. 2000 Plant and Environment, Pulawy, Poland, October 2-4. Plant health in polluted environment: Biochemical responses in environmental interactions. J.M. Lynch, M. Furmanowa, K. Glowniak and A.M. Zobel (invited speaker) 24. 2000 Trace ˙Elements in Food. Warsaw, Poland, October 9-10. Antioxidants, trace elements and whey protein. A.M. Zobel and M. Furmanowa (invited speaker) 25. 2000 3rd International Congress on Phytomedicine, Munich, Germany, October 11-13. Isolation of coumarins and other natural products from medicinal plants. K. Glowniak, M. Kozyra and A.M. Zobel 26. 2000 The Fight for Cancer Patients, Warsaw, October 14. Mixture of coumarin and taxol as a possible anticancer drug. A.M. Zobel and F. Graszyk 27. 2001 Ambermat, Gdansk, Poland, September 10. Amber in Canada. A.M. Zobel (invited speaker) 28. 2001 First European Allelopathy Society Meeting, Vigo, Spain. Zobel A.M., Lynch J. Deposition allelochemicals on plant surfaces. 2001 Ambermat, Gdansk, Poland, September 10. Amber in Canada. A.M. Zobel (invited speaker) 29. 2002 Poland, 3rd International Symposium on Chromatography of Natural Products. The application of chromatographic methods in phytochemical & biomedical analysis. June 12-15, Lublin- Kazimierz Dolny. – 30. Lynch J.M., Zobel A.M., Leaf morphological stage and phenolic concentration. (invited speaker). Zobel A.M., Białońska D., Banaś P2002: Glutathione in the cell (Poster). 31. 2002 3rd International Conference on Allelopathy. Tsukuba, Japan, 26-31 August 2002. Zobel A.M. Białońska D., 2002: Allelopathic concentrations of coumarins and other phenolic under stress conditions, and their histological localization. (invited speaker) Mineral Smart Inc. ~ 1-800-377-0084 PUBLICATIONS Peer-reviewed Orginal Publications (73) 1. Zobel, A.M., 1975. Mixoploidy of tannin coenocytes in Sambucus racemosa L. Acta Soc. Bot. Pol. 44: 491-500. 2. Zobel, A.M., 1977. Proteins present in tannin coenocytemother cells in Sambucus racemosa L. Acta Soc. Bot. Pol. 46: 47-55. 3. Podbielkowska, M., Zobel, A.M. and Waleza, M., 1980. Influence of cyclophosphamide on respiration and membrane permeability of plant cells. Acta Soc. Bot. Pol. 49: 357-361. 4. Tarkowska, J.A., Zobel, A.M. and Maciak, M., 1981. Development and transfer character of secretory glands in the broad bean, Vicia faba . Acta Soc. Bot. Pol. 50: 391-398. 5. Podbielkowska, M., Waleza, M. and Zobel, A.M., 1981. Influence of metho trexate on respiration and ultrastructure of meriste matic cells from Allium cepa roots. Acta Soc. Bot. Pol. 50: 563-566. 6. Zobel, A.M., 1985. Ontogenesis of tannin coenocytes in Sambucus racemosa L. I. Development of the coenocyte from mononucleate tannin cells. Ann. Bot. 55: 765-773. 7. Zobel, A.M., 1985. Ontogenesis of tannin coenocytes in Sambucus racemosa L. II.˙Mother tannin cells. Ann. Bot. 56:91-104. 8. Zobel, A.M., 1985. The internode of Sambucus racemosa L. originates from a single cell layer. Ann. Bot. 56: 105-107. 9. Zobel, A.M., 1986. Sites of localization of phenolics in tannin coeno cytes in Sambucus racemosa L. Ann Bot. 57: 801-810. 10. Zobel, A.M., 1986. Ontogenesis of tannin coenocytes in Sambucus racemosa L. III. The mature coenocyte. Ann. Bot. 58:849-858. 11. Hrazdina, G., Zobel, A.M. and Hoch, H.C., 1987. Biochemical, immuno logical, and immunochemical evidence for the association of chalcone synthase with endoplasmic reticulum membranes. Proc. Nat. Acad. Sci. U.S.A. 84: 8966-8970. 12. Zobel, A.M. and ˙Brown, S.A., 1988. Determination of furanocou marins on the leaf surface of Ruta graveolens with an improved extraction technique. J. Nat. Prod. 51: 941-946. 13. Zobel, A.M. and Brown, S.A., 1988. Furanocoumarins on plant˙surfaces. Proceedings ˙XIV International Conference of Groupe Polyphenols, Brock University, St. Catharines, Ontario, Canada, Aug. 16-19, 1988, Vol. 14, pp. 65-68. 14. Hrazdina, G., Zobel, A.M. and Hoch, H.C., 1988. Ultrastructural localization of chalcone synthase, a soluble flavonoid pathway enzyme, by ˙immunogold methods: Association with ER-membranes. Proceedings XIV International Conference of Groupe Polyphenols, Brock University, St. Catharines, Ontario, Canada, Aug. 16-19, 1988, Vol. 14, pp. 61-64. 15. Zobel, A.M., Kuras, M. and Tykarska, T., 1988. Phenolics-containing cells in embryos and seedlings. Proceedings XIV International Conference of Groupe Polyphenols, Brock University, St. Catharines, Ontario, Canada, Aug. 16-19, 1988, Vol. 14, pp 393-394. 16. Zobel, A.M. and Brown, S.A., 1989. Histological localization of furanocoumarins in R. graveolens shoots. Can J. Bot. 67: 915-921. 17. Zobel, A.M., 1989. Origin of nodes and internodes in plant shoots. I. Transverse zonation of apical parts of the shoot. Ann. Bot. 63: 201-208. 18. Zobel, A.M., 1989. Origin of nodes and internodes in plant shoots. II. Models of origin of nodes and internodes. Ann. Bot. 63: 208-220. 19. Zobel, A.M. and Brown, S.A., 1989. Localization of daphnetin and umbelliferone in different tissues of Daphne mezereum shoots. Can. J. Bot., 67: 1456-1459. 20. Zobel, A.M., Kuras, M. and Tykarska, T., 1989. Cytoplastic and apoplastic location of phenolic compounds in the covering tissue of the Brassica napus radicle between embryogenesis and germination. Ann. Bot. 64: 149-157. 21. Zobel, A.M. and Brown, S.A., 1990. Dermatitis-inducing furano coumarins on the leaf surfaces of eight species of rutaceous and umbelliferous plants. J. Chem. Ecol., 16: 693-700. 22. Zobel, A.M. and ˙Brown, S.A., 1990. Seasonal changes of furanocoumarin concentrations in leaves of Heracleum lanatum J.Chem. Ecol., 16: 1623-34. 23. Zobel, A.M. and Brown, S.A., 1991. Dermatitis-inducing psoralens on the surface of seven medicinal plant species. J. Toxicol., Cutaneous and Ocular Toxicol. 10: 223-231. 24. Zobel, A.M. and Brown, S.A., 1991. Psoralens in senes cing leaves of Ruta graveolens. J.Chem. Ecol. 17: 1801-10. Mineral Smart Inc. ~ 1-800-377-0084 25. Zobel, A.M. and Nighswander, J.E., 1991. Accumulation of phenolic compounds in the necrotic areas of Austrian and red pine needles due to salt spray. Ann. Bot. 66: 629-640. 26. Zobel, A.M. 1991. Effect of the change from field to greenhouse environment on the linear furanocoumarin levels of Ruta chale pensis . J. Chem. Ecol., 17: 21-27. 27. Zobel, A.M. and Brown, S.A., 1991. Psoralens on the surface of ˙seeds of ˙Rutaceae and fruits of Umbelliferae and Leguminosae. Can. J. Bot. 69: 485-488. 28. Hrazdina, G. and Zobel, A.M., 1991. Cytochemical localization of enzymes in plant cells. Cell Biol. 129: 269-322. 29. Zobel, A.M., Brown, S.A. and Nighswander, J.E., 1991. Effect of simulated acid spray on furanocoumarin concentrations on the surface of Ruta graveolens leaves. Ann. Bot. 67: 213-218. 30. Zobel, A.M., Kuras, M., Tykarska, T., Heneklaus, S. and Schnug, E., 1991. Leakage of fluorescent compounds from aging canola seeds as a method for distinguishing dead from living embryos. Proc. 8th Int. ˙Rapeseed Congr., Saskatoon, 5: 1430-1435. 31. Zobel, A.M., Brown, S.A. and March, R.E., 1991. Histological localization of psoralens in fruits of Psoralea bituminosa. Can. J. Bot. 69: 1673-1678. 32. Zobel, A.M., Wang, Y., March, R.E. and Brown, S.A. 1991. Iden tification of eight coumarins occurring with psoralen, xanthotoxin and bergapten on leaf surfaces. J. Chem. Ecol. 17: 1859-1870. 33. Zobel, A.M. and Hrazdina, G., 1992. Chalcone synthase localization in shoot apices of Fagopyrum, Brassica and Pisum .Ann. Bot. 70: 423-427. 34. Zobel, A.M. and March, R.E., 1993. Autofluorescence reveals different histological localization of furanocoumarins in fruits of some Umbelliferae and Leguminosae. Ann. Bot. 71: 252-255. 35. Zobel, A.M. and ˙Brown, S.A., 1993. Influence of low-intensity ultra violet radiation on extrusion of furanocoumarins to the leaf surface. J. Chem. Ecol. 19: 939-952. 36. Zobel, A.M. and Brown, S.A., 1993. Furanocoumarins on the surface of callus cultures from species of the Rutaceae and Umbelliferae. Can. J. Bot. 71: 966-969. 37. Zobel, A.M., 1993. Phenolic compounds: an answer by the plant to air pollution. Proceedings of Second Princess Chulab horn Meeting, Thai land. 38. Tkaczyk, M., Zobel, A.M., Plomley, J.B. and March, R.E., 1993. Mass spectrometric studies of selected coumarins and psoralens. Part I. Negative Ions. Organic Mass Spectrometry, 28: 1148-1154. 39. Zobel, A.M., Sandstrom, T., Nighswander, J.E. and Dudka, S., 1993. Uptake of metals by aquatic plants and changes in phenolic compounds. Heavy Metals in the ˙Environment, 1: 210-213. 40. Zobel, A.M., Brown, S.A., Kuras, M., Crang, R., Wierzbicka, M. and Nighswander, J.E., 1993. Some secondary metabolites altered by heavy metals. Heavy ˙Metals in the Environment, 1: 214-217. 41. Zobel, A.M., Chen, Y. and Brown, S.A., 1993. Influence of UV on furanocoumarins in Ruta graveolens leaves. Acta Hort., 40: 355-360. 42. Zobel, A.M., Crellin, J., Brown, S.A. and Glowniak, K., 1993. Concen trations of furanocoumarins under stress conditions and their histological localization. Acta Hort., 40: 510-516. 43. Zobel, A.M., Wronka, M., Tykarska, T., Kuras, M., Lewak, S. and Schnug, E., 1993. Localization of phenolic compounds in aging seeds of Brassica napus , and during their imbibition. Acta Hort. 40: 600-610. 44. Podbielkowska, M., Kupidlowska, E., Waleza, M., Dobrzynska , K., Louis, S.A., Keightley, A. and Zobel, A.M., 1994. Coumarins as antimitotics. Int. J. Pharmacog. 32: 1-12. 45. Wronka, M., Lewak, S., Tykarska, T., Kuras, M. and Zobel, A.M., 1994. Localization of phenolic compounds in the root cap colu mella of six-year-old dry seeds of Brassica napus during imbibition and germination. Ann. Bot. 74: 321-326. 46. Iwanowska, A., Tykarska, T., Kuras, M. and Zobel, A.M., 1994. Localization of phenolic compounds in the covering tissues of the embryo of Brassica napus during different stages of embryogenesis and seed maturation. Ann. Bot. 74: 313-320. 47. Kupidlowska, E., Kowalec, M., Sulkowski, G. and Zobel, A.M., 1994. The effect of coumarins on root elongation and ultra structure of meristematic cell protoplasts. Ann. Bot. 73: 525-530. 48. Zobel, A.M. and Hrazdina, G., 1994. Chalcone synthase localization in early stages of plant development. I. Immunohistochemical method employing plasmolysis for localization of the enzyme in cytoplasm of epidermal cells of illuminated buck wheat hypocotyls. Biotechnic and Histochemistry 70: 1-6. 49. Kupidlowska, E., Dobrzynska, K., Parys, E. and Zobel, A.M., 1995. Effect of coumarin and xanthotoxin on oxygen uptake and succinate dehydrogenase activity in plant meristematic cells. J. Chem. Ecol. 20: 2471-2480 50. Podbielkowska, M., Piwocka, M., Waszkowska, E., Waleza, M. and Zobel, A.M., 1995. Effect of coumarin and its derivatives on mitosis and ultrastructure of meristematic cells. Int.J. Pharm. 33: 7-15. 51. Lukasiak, J., Dejneka, W. and Zobel, A.M., 1996. Usage of speciation analysis in investigation of influence of air pollu tion on medicinal plants. Chemical Analysis 10: 1-5. Mineral Smart Inc. ~ 1-800-377-0084 52. Furmanowa, M., Glowniak, K., Zobel, A.M., Guzewska, J.G., Zgorka, L., Rapczewska, L. and Josefczyk, A., 1996. Taxol in Taxus baccata L. var. Elegantissima organs in tissue culture. Med. Fac. Landbow. Univ. Gent 60: 2115-2119. 53. Bieganowska, M.L., Petruczynik, A. and Zobel, A.M., 1996. Retention parameters of coumarins, flavonoids and anthocyanins in binary RP-HPTLC systems. J. Chromatog. 9: 273-279. 54. Podbielkowska, M., Waleza, M., Dobrzynska. K. and Zobel. A.M., 1996. Effect of two furanocoumarins and three other coumarins on ultrastructure, ATP-ases and acid phosphatases in meristematic cells of Allium cepa root tips. Int. J. Pharmacogn. 34: 96-104. 55. Keightley, A.M., Dobrzynska, M., Podbielkowska, M., Renke, K. and Zobel, A.M., 1996. Coumarin and its 4- and 7-substituted derivatives as retardants of mitoses in Allium root promeristem. Int. J. Pharmacogn. 34: 105-113. 56. Lukasiak, J., Dejneka, W., Zobel, A.M. and Wierzchowska-Renke, K., 1996. The use of speciation analytics to the study of the impact of environmental pollution on medicinal plants. Chem. & Ecol. Jugena 3: 41-47. 57. Zobel, A.M., Clarke, P.A. and Lynch, J.M., 1996. UV-absorbing compounds as protective shield due to UV-A radiation. Herba Polonica 42: 278-282. 58. Lynch, J.M., Wierzchowska-Renke, K. and Zobel, A.M., 1996. Short and long-term influence of UV-A radiation on Brassica oleracea. Herba Polonica 42: 248-251. 59. Zobel, A.M. and Lynch, J.M., 1996. Differences in biological activity of compounds extruded to the plant surfaces and those located inside the plant. Herba Polonica 42: 262-268. 60. Wierzchowska-Renke, K., Zobel, A.M. and Glowniak, K., 1996. Volatile oil, furanocoumarins and some microelements content of Archangelica litoralis Fr. Ann. Acad. Med. Gdansk 26: 163-173. 61. Stafanowska, M., Amarowicz, R., Kozlowska, H., Tykarska, T., Kuras, M. and Zobel, A., 1996. Biochemical and ultrastructural analysis of phenolic compounds in maturing ˙rape (Brassica napus) seeds. Herba Polonica 42: 273-277. 62. Glowniak, K., Wierzchowska-Renke, K. Kozyra, M. and Zobel, A.M., 1996. Influence of UV radiation on the content and localization of furanocoumarins in Ruta graveolens L. herb. Herba Polonica 42: 303-308. 63. Zobel, A.M., M. Furmanowa and K. Glowniak, 1997. Taxol on the surface of several yew species. Phytomedicine 9: 10-15. 64. Wierzchowska-Renke, K., M. Kozyra, K. Glowniak and A.M. Zobel, 1997. Influence of fertilizers containing Cu and Mn ions on the amount of furanocoumarins and bioelements in the fruits of Pastinaca sativa L. Herba Polonica 43: 404-411. 65. Zobel, A.M., A. Zalewski, K.W. Renke and K. Glowniak 1998. Influence of UV-radiation on xanthotoxin and bergapten content in Ruta graveolens L. and Angelica archangelica L. seedlings. Allelopathy Journal 5: 183-189. 66. Zobel, A.M., Plaxton, W. and Lazaruk, L., 1998. Cytological localization of aldolase by immunogold labelling in root tip cells of Brassica napus irradiated by UV-A. ˙Herba Polonica ˙42: 10-20. 67. Zobel, A.M., Renke, K. and Glowniak, K., 1998. Coumarins on the surface of Ruta graveolens roots. J. Chem. Ecol. 68. Zobel, A.M. and Clarke, P., 1999. Production of phenolics in seedlings of Acer saccharum and Acer platanoides in response to UV-A irradiation and heavy metals. Allelopathy J. 6, 21-34. 69. Glowniak, K., Mroczek, T. and Zobel, A.M., 1999. Seasonal changes in the concentrations of four taxoids in Taxus baccata L. during the autumn-spring period. Phytomedicine 6: 135-140. 70. Kuras, M, Stefanowska-Wronka, M., Lynch, J.M. and Zobel, A.M., 1999. Cytochemical localization of phenolic compounds in columella cells - Changes in the localization of phenolic compounds during germination. Ann. Bot. 84: 135-143. 71. Pietrosiuk, A., Furmanowa, M., Zobel, A.M., Kuras, M. and Michalak, A., 1999. "Cytochemical changes in meristematic cells of Allium cepa L. root tip treated with extracts from callus of Catharanthus roseus (L.) G. Don. Acta Soc. Bot. Pol. 68: 109-118. 72. Hopkala, H., Josefczk, A., Lobarzewski, J. and Zobel, A. The influence of iodine ions on the activity of soluble peroxidase. Protection of Environment and Natural Resources 8:395-402. 73. Wierzchowska-Renke, K., Zobel, A., Dorosz, A. and Glowniak, K., 1999. Changes in the mineral composition of medicinal plants caused by UV (366 nm) radiation and pests. Protection of Environment and Natural Resources 8: 125-134. 74. Zobel, A.M., Nighswander, J.E. Cybulski, K., Lynch, J.M., Wierzchowska-Renke, K., Glowniak, K., Furmanowa, M. and Kuras. M., 1999. Influence of acidification of Clear Lake and the surroun ding soil on the chemistry of medicinal plants growing in the lake or under undisturbed old-growth forests. Pol. J. Environmental Stud. 8: 61-67. Mineral Smart Inc. ~ 1-800-377-0084 75. Zobel, A.M., Kuras, M. Furmanowa, M., Gajdzis-Kuls, D., Tykarska, T. and Wierzchowska-Renke K., 1999. Effect of copper, manga nese and zinc on meristematic cells of root tips and leaves of Withania somnifera (L.) Dun. Pol. J. Environmental Stud. 8: 147-153. 76. Zobel, A.M. and Schellenberger, S.E., 2000. Paclitaxel in combination with coumarin as a potentially effective anticancer agent. Pharmaceutical Biology 38: 192-196. 77. Furmanowa M., Kropczyńska D., Zobel A., Głowniak K., Oledzka H., Józefowicz J., Sahajdak A., Józetczyk A., 2002. Influence of water extracts from the surface of two yew (Taxus) species on mites (Tetranychus urtices). J. Appl. Toxicol. 22: 107-109. 78. Majewska A., Furmanowa M., Głowniak K., Guzewska J., Zobel A., Kuraś M., 2002: Influence of extract from shoots of Taxus baccata var. elegantissima on ultrastructure and tubulin cytoskeleton of meristematic cells of Allium cepa L. roots. Acta Soc. Bot. Pol. 71: 211-221. Review Articles 1) Zobel, A.M., 1996. Coumarins in fruits and vegetables, pp. 173-203. (ed.) F.A. Tomas Barbern, Phytochemistry of Fruit and Vegetables. Oxford, London. 2) Zobel, A.M., 1996. Phenolic compounds as bioindicators of air pollution, pp. 100-130. (eds.) Yunus and Iqbal, Plant Response to Air Pollution. Wiley, Chichester. 3) Zobel, A.M. and Lynch, J.M., 1996. Shield against ultraviolet radiation causes production of both phytoalexins and allelochemicals. (ed.) F.A. Macias. Allelopathy, 4) Zobel, A.M. 1997. Coumarins in fruit and vegetables. in "Phytochemistry of Fruit and Vegetables", pp. 173-203, ed. Tomas-Barbaran, F.A. and Robins, R.J., Clarendon, Oxford. 5) Lynch, J.M. and A.M. Zobel 1998. Photostability of coumarins. in "Photoreactivity and Photostability of Drugs", pp. 100-110, ed. Felini, J., Royal Society of Chemistry, Oxford. 6) Wierzchowska-Renke,, K., A.M. Zobel and J. Kosinski 1998. Correlation of concentrations of flavonoids and some elements due to environmental conditions. in "Recycling of Trace Elements", pp. 252-255, ed. J. Oleszkiewicz, Ecopartner, Warsaw. 7) Zobel, A.M. 1998. Allelochemical function of coumarins on the plant surface. in "Principles and Practices in Chemical Ecology", pp. 20-45, ed. Interjit, S. and Dakshini, A. and Foy, A., CRC, Boca Raton, Florida. 8) Zobel, A.M., P.A. Clarke, J.M. Lynch, M. Kuras, T. Tykarska and E. Kupidlowska 1998. The production of phenolic compounds in response to UVA irradiation and metal ions in seedlings of Acer saccharum in "Recycling of Trace Elements", pp. 141-147, ed. J. Oleszkiewicz, Ecopartner, Warsaw. 9) Zobel, A.M.,1999. Allelochemical function of coumarins on the plant surface. In Principles and Practices of Plant Ecology, eds. Inderjit, K.M.M. Dakshini and C.L. Foy. CRC Press, Boca Raton, pp. 439-449. 10) Zobel, A.M. and ˙Lynch, J.M., 1999. Shielding against ultraviolet radiation causes production of both phytoalexins and allelochemicals. In Recent Advances in ˙Allelopathy, eds. F.A. Macias, J.C.G. Galindo, J.M.G. Molinillo and H.G. Cutler. Servicio de Publicationesú--úUniversidad de Cadiz, pp. 219-230. 11) Zobel, A.M., Clarke, P.A. and Lynch, J.M., 1999. Production of phenolics in response to UV irradiation and heavy metals in seedlings of Acer species. In Recent Advances in Allelopathy, eds. F.A. Macias, J.C.G. Galindo, J.M.G. Molinillo and H.G. Cutler. Servicio de Publicationesú--úUniversidad de Cadiz, pp. 231-242. 12) Zobel, A.M., 1999. Coumarins on the plant surface as antimitotics; Photochemistry and Photostability of Drugs, ed. A. Alliota. CRC Press, Boca Raton, pp. 10-26. 13) Zobel, A.M., 1999. Cedarite and other fossil resins in Canada. In Investigations Into Ambers, eds. B. Kosmowska-Ceranowicz and H. Paner. Archives of Museum Gdansk, 241-246. 14) Lynch, J.M. and Zobel, A.M., 2000. Ecological consequences of enhanced UV radiation on the phenolic content of Brassica oleracea: A review. In ˙Remediation Engineering of Contaminated Soils, eds. D.M. Wise, D.J. Trantolo, E.J. Cichon, H.I. Inyang and U. Stott meister. Marcel Dekker, New York, pp. 329-355. 15) Zobel A.M., Silva C., Lynch J., Brown S.A., Kozyra M., Miazga A., Głowniak K., Furmanowa M., Wierzchowska-Renke K., Kuraś M., Białońska D., 2002: Allelopathic concentrations of coumarins and other phenolic under stress conditions, and their histological localization. In: Reigosa M.J., Pedrol N., (ed.): Allelopathy. From molecules to ecosystems. Science publishers, Inc. Enfield (NH) USA, Plymounth, UK. pp 59-69. Mineral Smart Inc. ~ 1-800-377-0084 Clinical Support of Nutritional Supplimentation 1. Anderson R.A. 1997. Nutritional factors influencing the glucose/insulin system: chromium. J. Am. Coll. Nutr., 16: 404-410. 2. Artee G.E., Sies H. 2001. The biochemistry of selenium and the glutathione system. Environ. Toxicol. Pharmacol., 10: 153-158. 3. Beyersmann D., Haase H. 2001. Functions of zinc signaling, proliferation and differentiation of mammalian cells. BioMetals, 14: 331-341. 4. El-Bayoumi K. 1999. Role of trace elements in coronary heart disease. Brit. J. Nutr., 81: 85-86. 5. Elliott J.L. 2001. Zinc and copper in the pathogenesis of amyotrophic lateral sclerosis. Prog. Neuro-Psychopharmacol., 25: 1169-1185. 6. Fields M. 1999. Role of trace elements in coronary heart disease. Brit. J. Nutr., 81: 85-86. 7. Forrer R., Gautschi K. Lutz H. 2001. Simultaneous measurement of the trace elements Al, As, B, Be, Cd, Co, Cu, Fe, Li, Mn, Mo, Ni, Rb, Se, Sr and Zn in human serum and their reference ranges by ICP-MS. Biol. Trace Elem. Res., 80: 77-93. 8. Hamilton I.M.J., Gilmore W.S., Strain J.J. 2000. Marginal copper deficiency and atherosclerosis. Biol. Trace Elem. Res., 78:179-189. 9. Harris E.D. 2001. Copper homeostasis: the role of cellular transporters. Nutr. Rev., 59: 281-285. 10. Hirayama K., Yasutake A. 1998. Free radicals and trace elements. J. Trace Elem. Exp. Med., 11: 209-217. 11. Kleszczewska E. 2001. Rola witaminy C we wchłanianiu I wydalaniu metali. Pol. Merk. Lek., 11: 539-542. 12. Linshaw M., Aigbe M., Kaskel F. 1998. The mineral disorders in pediatrics. Semin. Nephrol., 18: 280-294. 13. Lukaski H.C., 2000. Magnesium, Zinc, and chromium natriture and physical activity. Am. J. Clin. Nutr., 72 (suppl.): 585S-593S. 14. Nielsen F.H. 2000. Possibly essential trace elements. In: Clinical Nutrition of the Essential Trace Elements and Minerals: The Guide for Health Professio-nals. (Ed. J.D. Bogden and L.M. Klevay), Humana Press, Totowa, N.J., 11-36. 15. Nishi Y. 1996. Zinc and growth. J. Am. Coll. Nutr., 15: 340-344. 16. Nordberg G., Sandström B., Becking G., Goyer R.A. 2000. Essentiality and toxicity of trace elements: principles and methods for assessment of risk from human exposure to essential trace elements. J. Trace Elem. Exp. Med., 13:141-153. 17. Olędzka R. 1999. Wpływ metali i innych substancji obcych na biodostępność mikroelementów. Bromat. Chem. Toksykol., 32: 207-213. 18. Ovesen J., Møller-Madsen B., Thomsen J.S., Danscher G., Mosekilde L.I. 2001. The positive effects of zinc on skeletal strength in growing rats. Bone, 29: 565-570. 19. Peng X., Lingxia Z., Schrauzer G.N., Xiong G. 2000. Selenium, boron and germanium deficiency in the etiology of Kashin-Beck disease. Biol. Trace Elem. Res., 77: 193-197. 20. Rico H., Villa L.F. 2000. Zinc, a new coherent therapy for osteoporosis? Calcif. Tissue Int., 67:422-423. 21. Solomons N.W., Ruz M. 1998. Trace element requirements in humans: an update. J. Trace Elem. Exp. Med., 11: 177-195. 22. WHO. Trace elements in human nutrition and health. Geneva 1996. Mineral Smart Inc. ~ 1-800-377-0084 Minerals and Human Health I'd like to quote from U.S.A. Senate Document Number 264: "It is bad news to learn from our leading authorities that 99% of the American people are deficient in these minerals, and that a marked deficiency in any one of the more important minerals actually results in disease." I have been teaching this to my patients for nearly 20 years, and I am glad to see the importance of the minerals in foods finally being recognized. Even the disposition and learning capabilities of children are dependent upon a healthy diet and an adequate intake of minerals, including the macro-, micro- and trace elements. Electrolytes support immune system functions and heart health. Low levels of some electrolytes have been linked with mental confusion and behavioral problems. Electrolytes are found best in raw foods, which are "live" foods. Cooked foods lose the life principles and are referred to as "dead" foods. Our ancestors probably got all or most of their mineral elements from pure drinking water. This is no longer possible for most people. We need to make up the difference by using only foods grown on mineral-rich soils or by taking a reliable supplement. Our blood and lymph are loaded with mineral salts. Distribution of minerals in the human body: • Macroelements (oxygen 48 000 g) • Microelements (zinc 2 g) • Trace elements (cobalt 0.002 g) • The body is an electromagnetic organism. • The great Midwest flood of 1993 robbed the U.S. of 100 times the normal annual erosion, representing six billion tons in the state of Mississippi alone. • In the U.S., the topsoil has been reduced from an average of 1.5 meters to 0.15 meters in the last century. • Erosion has removed minerals to the ocean so that it contains 44 in abundance and virtually monopolizes 20 of these elements. • Even drinking too much water can flush out excessive electrolytes, causing an imbalance in the homeostasis of the body. • Mortality rates of white males (age 35-74) are twice as high in the Southeast than the Midwest U.S., likely due to lack of minerals (selenium, zinc, magnesium and chromium) in soil and water. • Comparing refined white sugar to raw brown sugar we lose: • 1. 92% of chromium • 2. 67% of zinc • 3. 88 % of cobalt • 4. 57 % of copper What an incredible waste! Info by: Dr. A. Zobel PhD. Mineral Smart Inc. ~ 1-800-377-0084